How long should clopidogrel be given along with aspirin after angioplasty and drug-eluting stent placement?

Dual antiplatelet therapy with aspirin and clopidogrel is recommended for 12 months for patients with drug-eluting stents and for at least 1 month for bare metal stents and preferably for 1 year.

Can clopidogrel and aspirin be given together?

The combination of aspirin and clopidogrel is not recommended for routine use for any longer than 12 months after the acute phase of myocardial infarction (MI), unless there are other indications to continue dual antiplatelet therapy, and the combination is usually recommended for a shorter duration after an ST-segment …

When should I restart aspirin and Plavix after surgery?

It is recommended that warfarin be resumed 12 to 24 hours after surgery; rivaroxaban, apix- aban, and dabigatran can be resumed 2 to 3 days postop- eratively; aspirin and clopidogrel can be resumed 24 hours after surgery.

Why do drug-eluting stents require longer antiplatelet therapy?

Drug-eluting stents A longer duration of combination antiplatelet therapy is required because the drug in the stent delays endothelialisation. Initial data from trials suggested clopidogrel be continued for a minimum of 3—6 months following implantation of a stent.

How long do you take Plavix after drug-eluting stent?

Background: American and European cardiology societies recommend six to 12 months of dual-antiplatelet therapy with aspirin and clopidogrel (Plavix) after drug-eluting stent placement to prevent late stent thrombosis.

How long do you have to take Plavix after stent placement?

It has been common practice for patients who have had a stent placed to clear a blocked artery to take an anti-clotting drug (such as Plavix, Effient, or Brilinta) plus aspirin for 12 months after the procedure. Taking these two medications, called dual anti-platelet therapy, reduces the risk of forming blood clots.

When is the best time to take Plavix and aspirin?

Conclusion: Taking aspirin and clopidogrel at 20:00 was superior to taking the same medications at 8:00 for inhibiting peak platelet aggregation in the morning.

Why is Plavix taken with aspirin?

However, they act in different ways, and just because you take one doesn’t mean you shouldn’t take the others. Aspirin and clopidogrel (Plavix) help stop platelets from clumping together inside your arteries. This reduces the chances that an artery-closing clot will develop on or near your stent.

How long after surgery can you resume aspirin?

For patients on a long-term aspirin regimen, the most effective time to restart aspirin would be 8 to 10 days after surgery, when the bleeding risk has diminished considerably.

When is it safe to restart anticoagulation after surgery?

Restarting warfarin and postoperative bridging – We resume warfarin 12 to 24 hours after surgery, typically the evening of the day of surgery or the evening of the day after surgery, assuming there were no unexpected surgical issues that would increase bleeding risk and the patient is taking adequate oral fluids [8].

How long should you stay on Plavix after a stent?

The data “suggest that all patients with drug-eluting stents should continue to take [Plavix] for at least 12 months after [stent implantation], and possibly indefinitely,” Eisenstein and colleagues conclude.

When do you stop clopidogrel after a stent?