What is the structural formula of codeine?

What is the structural formula of codeine?

C18H21NO3Codeine / Formula

What are the properties of codeine phosphate?

Codeine phosphate is an opioid analgesic with uses similar to those of morphine, but is much less potent as an analgesic. Its primary site of action is at the mu opioid receptors distributed throughout the central nervous system. The sedative activities of codeine are less potent than those of morphine 13.

What type of bond is codeine?

In COP-H, two cations are linked together through (codeine)–O–H⋯O–(codeine) hydrogen bonds, employing the hydroxy and methoxy groups, the hydroxy group is additionally bonded to the water molecule and moreover, both codeine cations are bonded to the phosphate anions via (codeine)–N–H⋯O–(phosphate) hydrogen bonds (Fig.

What is the main chemical in codeine?

The phosphate salt of codeine, a naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities….codeine phosphate.

Synonym: tricodein
Chemical structure: morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5-alpha,6-alpha)-, phosphate

What is codeine phosphate soluble in?

Solubility of codeine phosphate in carbitol + 2-propanol mixture at different temperatures.

What is c18h21n1o3?

(-)-codeine | C18H21NO3 | ChemSpider.

What is codeine phosphate?

A drug used to treat pain, cough, and diarrhea. It is made from opium or morphine and binds to opioid receptors in the central nervous system. Codeine phosphate is a type of opiate, a type of analgesic agent, a type of antitussive agent, and a type of antidiarrheal agent.

Is codeine phosphate basic or acidic?

Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing….Structure for Codeine phosphate (DBSALT000030)

Property Value Source
pKa (Strongest Acidic) 13.78 ChemAxon
pKa (Strongest Basic) 9.19 ChemAxon

Is codeine phosphate a salt?

Codeine Phosphate is the phosphate salt of codeine, a naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities. Codeine mimics the actions of endogenous opioids by binding to the opioid receptors at many sites within the central nervous system (CNS).

What is CH2NO3?

Hydroxycarbamate | CH2NO3 | ChemSpider.

What is the name of C7H8N4O2?

Theobromine | C7H8N4O2 – PubChem.

What is the molecular formula for codeine phosphate?

Molecular Formula. C36H50N2O15P2. Synonyms. 41444-62-6. UNII-GSL05Y1MN6. Codeine phosphate hemihydrate. GSL05Y1MN6. Codeine phosphate hydrate. More…

What is the chemical name for codeine hydrochloride?

Codeine hydrochloride is more common worldwide and the citrate, hydroiodide, hydrobromide, tartrate, and other salts are also seen. The chemical name for codeine is morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)-.

What is the pKa of codeine in organic chemistry?

The pKa of codeine is 8.21 (3), indicating that this compound will exist almost entirely in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts (4).

What is the patent number for codeine synthesis from morphine?

Retrieved 29 December 2019. ^ Corcoran, R. C.; Ma, J. Solid-phase synthesis of codeine from morphine. NV, United States Patent 6,204,337, 2001. ^ The American Practitioner. 1912. ^ Fraser, Thomas R (1889). “The Relative Value of Opium, Morphine, and Codeine in Diabetes Mellitus”.