What are chief cells and parietal cells?

Chief cells produce pepsinogen, which is converted to pepsin by hydrochloric acid in the stomach. Parietal cells produce hydrochloric acid, allowing this conversion. Goblet cells produce the mucous lining of the stomach that protects the stomach epithelium from damage from the acidic environment of the gastric lumen.

What is the histology of the stomach?

It stands for: Mucosa, Submucosa, Muscularis externa & Serosa. Although the stomach is anatomically divided into four regions, histologically we identify only three; cardia, fundus and pylorus.

What is Fundic region?

fundus: dome-shaped region of the stomach above and to the left of the cardia. G cell: gastrin-secreting enteroendocrine cell. gastric emptying: process by which mixing waves gradually cause the release of chyme into the duodenum. gastric gland: gland in the stomach mucosal epithelium that produces gastric juice.

Which cells are present in stomach?

Four different types of cells make up the gastric glands:

• Mucous cells.
• Parietal cells.
• Chief cells.
• Endocrine cells.

What is chief cell of stomach?

The gastric chief cell (also known as a zymogenic cell or peptic cell) is a cell in the stomach that releases pepsinogen and chymosin. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with hydrochloric acid produced by gastric parietal cells.

What do the chief cells of the stomach secrete?

Pepsinogens
Pepsinogens are synthesized and secreted primarily by the gastric chief cells of the human stomach before being converted into the proteolytic enzyme pepsin, which is crucial for digestive processes in the stomach. Furthermore, pepsin can activate additional pepsinogen autocatalytically.

What layer of the stomach wall has the parietal and chief cells?

mucosa
Gastric glands comprise the bulk of the mucosa beneath the pits. Although lamina propria separates the individual glands, most of the mucosal volume is occupied by secretory cells, primarily parietal cells and chief cells. The submucosa of the stomach is relatively unspecialized.

What do chief cells secrete?

pepsinogen
The chief cells secrete pepsinogen, a moderately sized zymogen protein with a molecular weight of 40,400. Pepsin, an enzyme with a molecular weight of 32,700, is formed in the acidic environment of the stomach when pepsinogen loses its activation peptides.

What are chief cells?

Finally, the chief cells (zymogenic) are basophilic cells that are located in the bottom of the gland and which produce different gastric enzyme precursors, such as pepsinogen.

What is fundus in stomach?

Fundus. The fundus is the enlarged portion to the left and above the cardiac orifice.

What do chief cells produce?

The gastric chief cell (also known as a zymogenic cell or peptic cell) is a cell in the stomach that releases pepsinogen and chymosin. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with hydrochloric acid produced by gastric parietal cells.

What is the function of the chief cell?

The primary function of gastric chief cells is the synthesis and release of the proenzyme pepsinogen, which subsequently, in an acid environment, is converted to the acid protease pepsin.

Where is the stomach of a frog?

The stomach of frog lies in the left side in the body cavity. It is attached to the body wall by a mesentery called mesogastor.mesogastor is the large (4cm), broad, and slightly curved bag or tube with thick muscular walls.

What is the physiology of digestion in frog?

Physiology of digestion in frog: Being strictly carnivorous, frog feeds on insects, worms, crustaceans, molluscs, small fish and even small frogs and tadpoles. The prey is caught by rapid flicking of tongue and is swallowed as a whole. The food is now passed to stomach.

What is the anatomy of a frog?

The characteristic features of these amphibians include short bodies, the absence of tail, long hind legs that allow them to leap, webbed fingers and toes, and protruding eyes. The anatomy of frogs has been of interest to humans due to the striking similarities in the organ systems of frogs and humans. Frogs have a single body cavity in the trunk.

What is the function of the pancreas of frog?

1 Pancreas of frog is much branched, irregular flattened and is yellow in color. 2 It lies in the mesentery between stomach and duodenum. 3 It carries out both exocrine and endocrine function. 4 The endocrine part is formed by scattered islets of Langerhans. 5 The exocrine part secretes pancreatic juice.