Which drug interacts with digoxin?

Which drug interacts with digoxin?

Digoxin has many interactions, including:

  • Erythromycin and tetracycline (antibiotics)
  • Antiarrhythmic drugs (amiodarone)
  • Calcium channel blockers.
  • Over-the-counter antacids.
  • Hawthorn (an herbal remedy)
  • Black licorice.
  • Large amounts of oatmeal, milk and high-fibre cereals.

What medications need to be monitored carefully if given to a patient who has renal insufficiency?

Problematic drugs whose use in patients with renal insufficiency is nephrologically contraindicated: Pethidine, cefepime, lithium, gilbenclamide, gimepiride, metformin, spironolactone, eplerenone, methotrexate, gadolinium, enoxaparin.

Why timolol eyedrops and salbutamol inhaler should not be used at the same time?

Using timolol ophthalmic together with albuterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, timolol ophthalmic can sometimes cause narrowing of the airways, which may worsen your breathing problems or trigger severe asthmatic attacks.

What medications interact with brimonidine?

Some products that may interact with this drug include: beta-blockers (such as atenolol, metoprolol, timolol eye drops), digoxin, high blood pressure medications (such as clonidine, terazosin), tricyclic antidepressants (such as amitriptyline).

What is contraindicated with digoxin?

Digoxin is contraindicated in the following conditions[5]: Acute myocardial infarction. Hypersensitivity to the drug. Ventricular fibrillation.

What does digoxin react with?

The adverse effects of digoxin are potentiated by renal impairment, which may be pre-existing or due to nephrotoxic drugs such as nonsteroidal antiinflammatory drugs (NSAIDs), angiotensin-converting-enzyme (ACE) inhibitors, angiotensin II receptor antagonists and ciclosporin.

What medications should be avoided with renal failure?

What medications to avoid with kidney disease

  • Pain medications also known as nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Proton pump inhibitors (PPIs)
  • Cholesterol medications (statins)
  • Antibiotic medications.
  • Diabetes medications.
  • Antacids.
  • Herbal supplements and vitamins.
  • Contrast dye.

Which medications are nephrotoxic?

Drugs Associated with Nephrotoxicity

Drug class/drug(s) Pathophysiologic mechanism of renal injury
Pamidronate (Aredia) Glomerulonephritis
Phenytoin (Dilantin) Acute interstitial nephritis
Quinine (Qualaquin) Thrombotic microangiopathy
Ranitidine (Zantac) Acute interstitial nephritis

Can eye drops cause breathing problems?

Systemic absorption of /3-antagonist eye drops can cause unsuspected respiratory impairment. Physicians should be alert to the possibility of respiratory side-effects of topical therapy with /3-antagonists and whenever such side-effects occur should use alternative treatments.

Why is timolol not used in asthmatic patients?

International guidelines recommend that beta‐blockers are contraindicated in asthma over safety concerns regarding acute bronchoconstriction 1, 2, 3. This effect results from endogenous and exogenous catecholamine antagonism at the pulmonary beta2‐adrenoceptor leading to unopposed cholinergic tone.

Does brimonidine affect the heart?

Blood pressure and heart rate decreased significantly in the brimonidine group compared with placebo.

Does brimonidine raise blood pressure?

Severe cardiovascular (heart) disease: Although brimonidine typically has little effect on blood pressure and heart rate, it may lower blood pressure and heart rate (pulse) if you have severe heart disease.

What are digoxin nursing implications?

Digoxin nursing implications are divided into nursing assessment, interventions, and evaluation. Take a comprehensive medical, drug, and herbal history. Determine the previous hypersensitivity to digoxin and related ingredients and possible food interactions. Obtaining a baseline vital signs for future comparison including apical pulse.

What are the side effects of Travatan?

Common Travatan side effects may include: 1 pain, itching, or redness of the eyes; 2 puffy eyelids; or 3 blurred vision.

What should be included in patient education about digoxin toxicity?

Additional considerations include informing patients on the effect that medications, even over-the-counter ones, and diet have on how digoxin is absorbed in the body. For example, a diet high in fiber can actually decrease the amount of digoxin that is absorbed before it’s eliminated from the body.

How does Travatan work to reduce pressure in eye?

It works to reduce pressure in the eye by increasing the amount of fluid that drains from the eye.. Travatan eye drops are used to treat open-angle glaucoma and other causes of high pressure inside the eye (ocular hypertension).